Drug Repositioning Approaches And Applications For Neurotherapeutics (Hb 2017) Hardcover

Nervous system diseases pose a significant global health challenge. Despite substantial financial and professional investment, their causes and underlying mechanisms remain largely unknown, and there is still an unmet clinical need for disease-modifying treatments. In recent years, traditional research and development have struggled to identify new effective therapies in many areas of medicine, leading to the emergence of drug repositioning as a promising strategy to enhance and expedite therapeutic development, offering an alternative to de novo drug discovery. For the first time, Drug Repositioning: Approaches and Applications for Neurotherapeutics examines the history and progress of drug repositioning, with a particular emphasis on therapies for nervous system disorders. This book gathers insights from international experts in academia, industry, and non-profit organizations, exploring the advantages, challenges, and specific applications of drug repositioning in diseases such as Alzheimer's, Parkinson's, Huntington's, Amyotrophic Lateral Sclerosis, Spinal Muscular Atrophy, ischemic stroke, and psychiatric disorders. Providing a comprehensive overview, this book synthesizes the concept, methods, and applications of drug repositioning in neurotherapeutics. It serves as a valuable resource for students, scientists, and clinicians in academia, industry, and government agencies within the fields of neuroscience, pharmacology, neurology, pharmaceutical sciences, and drug discovery and development.