Genome Duplecation: Concepts, Mechanisms, Evolution & Disease Paperback

"Genome Duplication" offers a clear and thorough exploration of the fundamental processes that control how genetic material is copied in all living things, from single-celled organisms to complex animals and plants.   Drawing examples from bacteria, archaea, and eukaryotes, the book illustrates that all life stores its genetic information as DNA and uses a remarkably similar, evolutionarily ancient method to duplicate it: the replication fork, which carries out semi-conservative DNA replication. The text explains how this replication fork dictates where genome copying begins, ensures a complete genome copy with each cell division, and coordinates genome duplication with the cell division cycle.   Furthermore, "Genome Duplication" highlights the connection between errors in this copying process and the development of genetic disorders and cancer. It emphasizes that understanding the mechanisms, regulation, and variations of genome duplication across different life forms is essential for comprehending and treating human diseases.