Toxicology Of The Gastrointestinal Tract 2Ed (Hb 2019) Hardcover

The gastrointestinal tract is a primary pathway for the absorption and elimination of foreign substances and biologic entities in mammals, making it a key route for drug administration in humans. Gastrointestinal Toxicology, Second Edition explores the mechanisms of entry and clearance of xenobiotics, as well as the various barriers, immune responses, metabolic processes, and functions present in the GI tract. The volume also examines the microbiome and its impact on GI function, as well as how it affects the toxicity and pharmacodynamics of substances such as nutrients, toxins, and pharmaceuticals. The book, with contributions from experts in the field, covers methods for assessing GI function, GI toxicity evaluation in canines and minipigs, the toxicity of different compound classes, species-specific differences, and the potential risks and benefits of nanoparticles. This comprehensive reference is essential for anyone seeking to understand the structure, function, and study methods related to the gastrointestinal tract.